Description
The main goals of Molecular Medicine Programme address the actual topics in current biomedical research and clinical medicine. They are focused on introduction of modern approaches of the genome analysis (human, as well as microbial), characterisation of cell behaviour on a molecular level, with emphasis on malignant transformation, and resistance to modern anti-cancer treatment, and analysis of mechanisms leading to disturbances of immune response.
| Topic | Supervisor |
|---|---|
| 1. BCR Signalling Pathway and its Crosstalk with Adhesion in the Biology of B-Cell Malignancies | Marek Mráz |
| 2. Elucidating role(s) of cyclin-dependent kinase 12 (Cdk12)in regulation of gene expression/DNA damage response using model of ovarian carcinoma | Dalibor Blažek |
| 3. Elucidating the biological role of the ‘epitranscriptome’ | Mary O’Connell |
| 4. Genomic analysis of leukemic cells using next generation sequencing approaches | Šárka Pospíšilová |
| 5. How did the DNA genome evolve from RNA? | Liam Keegan |
| 6. Non-Coding RNAS and Microenvironmental Interactions of B-Cell Leukemias and Lymphomas | Marek Mráz |
| 7. Ratiometric genetically encoded fluorescent sensors for measurement of intracellular pH values | Dmitriy Chudakov |
| 8. The role of RNA modification in innate immunity | Mary O’Connell |
| 9. Identification of genomic lesions in NGS data of leukemic cells for clinical applications | Vojtěch Bystrý |
| 10. High throughput sequencing data analysis of IG/TR rearranged genes in leukemia clinical research | Vojtěch Bystrý |
Requirements
Successful candidate must hold the equivalent of a Czech Master’s degree (Mgr., Ing., MSc.) in the same or similar study programmes from an institution of recognized standing (four or five year undergraduate degree).
Detailed information available HERE
Conditions and contact
Starting date: September 2017
Deadline for submitting complete applications: 28 February 2017
To apply please contact Olga Křížová on phd@ceitec.muni.cz
Information about Brno, Czech Republic
- The capital of South Moravian Region and the second largest city in the Czech Republic with a population of almost 400,000 people
- A city of universities with more than 86,000 students
- More than 10,000 researchers; 600+ PhD graduates/year
- City of Gregor Mendel, the founder of genetics
Information about Masaryk University
- The second largest university in the Czech Republic, consisting of nine faculties
- Extremely wide range of study possibilities
- State-of-the-art equipment, cutting-edge technologies and international cooperation
- A member of the Compostela Group and the Utrecht Network
