PhD: Multifunctional nanostructured biomaterials for adult stem cells : Karlsruhe, Germany

Work group:

Institute of Functional Interfaces (IFG)
Area of research:

PHD Theses
Job description:

Tätigkeitsbeschreibung: Aim of the research of the group of stem cell–material interactions is to develop artificial systems that mimic the natural environment of hematopoietic (= blood forming) stem cells, the ‘stem cell niche’. Beside biological processes (such as cell–cell and cell–matrix interactions), physical parameters including stiffness or nanopatterning of the environment play an important role in this niche. In the framework of a BMBF-funded project we are currently looking for a PhD candidate. The focus of this project is the development and testing of a novel multifunctional nanostructured biomaterials for hematopoietic stem cells. These stem cells are used for the treatment of patients with hematological disorders (such as leukemia) or might be beneficial after myocardial infarction. Therefore, they are of high clinical relevance.

This is an interdisciplinary project, in which methods of cell biology, chemistry, materials science, and biochemistry are applied. Innovative surface functionalization and patterning techniques will be applied and used to answer fundamental biological and biophysical questions.

Persönliche Qualifikation: Personal requirements: Applicants must have a university or master degree in the field of biology, biochemistry, biophysics or a similar field of study. In addition, the strong willingness and ability to work in a highly interdisciplinary team are expected. Some experience in cell culture or surface chemistry is a plus but not required. Institut/Abteilung: Institute of Functional Interfaces (IFG) Vertragsdauer: befristet for 3 years Eintrittstermin: as soon as possible Bewerbung bis: 01.03.2017 Ansprechpartner/in für fachliche Fragen: Fachliche Auskünfte erteilt Ihnen gerne Cornelia Lee-Thedieck, phone: +49-(0)721-608 23588; email: Bewerbung: Bitte senden Sie Ihre Bewerbung unter Angabe der Stellenausschreibungsnummer 02-2017 IFG an Frau Ratzel, HPS, Telefon 07247 82-25544.

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