Internships

Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg

Master Thesis

Job Offer from January 26, 2017

The Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg offers a Master Thesis or an Internship with the topic “Method development for the characterization of glycosyltransferases and in-vitro enzyme cascade”.

Glycosylation is an important modification of proteins, and is involved in the regulation of biological activity and stability of many proteins. Notably, the glycosylation of many eukaryotic proteins appears to be highly-regulated and minor structural changes of glycan portions may lead to enzyme dysfunction. Research into glycosylation has, thus, profoundly increased over the last years and controlling protein glycosylation is seen as a key for the cost-effective manufacturing of biotechnological products.  In a joint project, an in-vitro enzyme cascade is build up to produce glycans enzymatically. Detection and quantification of glycans and sugar nucleotides by high performance anion exchange chromatography (HPAEC) and high performance multiplexed capillary gel electrophoresis with laser-induced fluorescence detection (xCGE-LIF) requires highly efficient and novel methods. We offer an exciting project in the cross section of bioengineering and bioanalytics with the opportunity to work with state-of-the-art equipment and first-class training and supervision.

Requirements

  • background in biotechnology, chemical engineering or analytical chemistry
  • ideally, experience with bioanalytical methods
  • motivation, curiosity and ability to work in a team

We offer

  • exciting research projects and the opportunity to develop key technologies
  • first-class supervision and thorough training by our staff
  • training on state-of-the-art equipment for biotechnological research and development
  • acquisition of expertise in a key technology of the future

Application

Applications in German or English are welcome. Please include your CV and transcript of records.

Note that applications from women are especially welcome and that the Max Planck Society is committed to employing disabled individuals and encourages them to apply.

Start: March 2017. Contact: Dr. Thomas Rexer, phone: +49 (0) 391 6110 375.

Max Planck Institute for Dynamics of Complex Technical Systems
Sandtorstr. 1
39106 Magdeburg
Germany

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